Most cancers require at least two mutations: 1) one in an oncogene, which encodes proteins that trigger cell division, and 2) one in a tumor suppressor gene, whose protein products, in their unmutated form, play a key role in preventing the cell cycle from progressing if the dna is damaged or in the absence of specific cues. which class of proteins might be considered tumor suppressors?​

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​Cdk inhibitors is protein products, in their unmutated form, play a key role in preventing the cell cycle from progressing if the DNA is damaged or in the absence of specific cues.

• Genetic changes that either boost gene expression or cause uncontrolled activation of the oncogene-encoded proteins cause oncogenes to induce aberrant cell proliferation.

• The opposing side of cell growth control is represented by tumour suppressor genes, which typically operate to prevent tumour development and cell proliferation.

• These genes are frequently lost or inactivated in tumours, removing any inhibitors of cell growth and promoting the uncontrolled growth of tumour cells.

• The scientists found that two or more important gene alterations are typically required for cancer to develop.
• These mutations in a person may result from environmental factors, inherited genes, or accidental DNA copying errors.

To learn more about mutations.

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